material sample

IRI: https://spec.industrialontologies.org/ontology/construct/MaterialSample

Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaMonitoringAndControl/

SubClass Of: bfo:material entity

Class Hierarchy

owl:Thing › bfo:entity › bfo:continuant › bfo:independent continuant › bfo:material entity › material sample

Definition

material entity that is the specified output of a sampling proces

Semi-Formal Definition:

every instance of ‘material sample’ is defined as exactly an instance of ‘material entity’ that ‘is specified output of’ some ‘sampling process’

Examples

• A 10 mL aliquot of bioreactor culture collected during mid-log phase for cell viability analysis; a pre-filled vial of harvested supernatant taken from a chromatography pool for impurity testing; a powder sample taken from the middle of a drum of API to test for uniformity of composition; a tablet randomly selected from a production batch during compression for hardness testing

Formal Axioms

First-Order Logic Definition

MaterialSample(x) ↔ MaterialEntity(x) ∧ ∃s(SamplingProcess(s) ∧ isSpecifiedOutputOf(x, s))

Description Logic

constr:MaterialSample ≡ bfo:material_entity ⊓ ∃ constr:isSpecifiedOutputOf .constr:SamplingProcess

constr:MaterialSample ⊑ bfo:material_entity

EquivalentTo: bfo:material_entity and constr:isSpecifiedOutputOf some constr:SamplingProcess

SubClassOf: bfo:material_entity