critical process parameter
IRI: https://spec.industrialontologies.org/ontology/construct/CriticalProcessParameter
Defined In: https://spec.industrialontologies.org/ontology/biopharma/Parameter/
SubClass Of: process parameter
Class Hierarchy
owl:Thing › bfo:entity › process parameter › critical process parameter
Definition
process profile or temporal region or quality prescribed by a critical process parameter specification
Semi-Formal Definition:
every instance of ‘critical process parameter’ is defined as exactly an instance that is either a ‘temporal region’ or a ‘process profile’ or ‘quality’ and that is ‘prescribed by’ some ‘critical process parameter specification’
Explanatory Notes
See the expanded definition under the corresponding specification class. The term is formalized here as a defined class by referring to its corresponding specification class and exists primarily for ontological modeling and implementation convenience.
Examples
- pH during the viral inactivation process; temperature during the fermentation process; agitation speed during the cell culture mixing step
Formal Axioms
First-Order Logic Definition
CriticalProcessParameter(x) ↔ ∃s(CriticalProcessParameterSpecification(s) ∧ prescribedBy(x, s)) ∧ (TemporalRegion(x) ∨ ProcessProfile(x) ∨ Quality(x))
Description Logic
constr:CriticalProcessParameter ≡ (bfo:temporal_region ⊔ bfo:quality ⊔ bfo:process_profile) ⊓ ∃ constr:prescribedBy .constr:CriticalProcessParameterSpecification
EquivalentTo: (bfo:temporal_region or bfo:quality or bfo:process_profile) and constr:prescribedBy some constr:CriticalProcessParameterSpecification
SubClassOf: constr:ProcessParameter