monitoring process
IRI: https://spec.industrialontologies.org/ontology/construct/MonitoringProcess
Defined In: https://spec.industrialontologies.org/ontology/biopharma/MonitoringAndControl/
SubClass Of: planned process
Class Hierarchy
owl:Thing › bfo:entity › bfo:occurrent › bfo:process › planned process › monitoring process
Definition
planned process that is a part of another planned process and that consists of one or more observation or measurement processes in which a particular attribute (specifically dependent continuant or temporal region or process characteristic or process profile) of some entity of interest is measured or observed
Semi-Formal Definition:
every instance of ‘monitoring process’ is defined as exactly an instance of ‘planned process’ that ‘has occurrent part’ some ‘measurement process’, is ‘occurrent part of’ some ‘planned process’, and is ‘prescribed by’ some ‘monitoring plan’
Explanatory Notes
1)Each monitoring process is an execution of a monitoring plan that prescribes it 2) In case a monitoring process is responsible for monitoring the attribute/parameter/indicator in multiple processes (e.g., multiple unit operations) it is a part of the ‘larger process’ which has the ‘occurrent part’ the unit operations and it does not imply that it is an occurrent part of the unit operations themselves”.
Examples
- UV absorbance and conductivity monitoring during column loading; continous monitoring of temperature and humidity in a clean room; Tablet weight is measured in-line every 30 minutes during compression using an integrated balance; During a fed-batch cell culture process, at-line nutrient monitoring is performed using a Nova BioProfile® FLEX analyzer to measure glucose, lactate, glutamine, and ammonia levels; Flow rate is continuously monitored during tangential flow filtration to ensure consistent membrane performance
Synonyms
- process monitoring
Adapted From
- https://www.biopharminternational.com/view/monitoring-biopharmaceutical-processes-present-and-future-approaches
Formal Axioms
First-Order Logic Definition
MonitoringProcess(x) ↔ PlannedProcess(x) ∧ ∃m(MeasurementProcess(m) ∧ hasOccurrentPart(x, m)) ∧ ∃p(PlannedProcess(p) ∧ occurrentPartOf(x, p)) ∧ ∃mp(MonitoringPlan(mp) ∧ prescribedBy(x, mp))
Description Logic
constr:MonitoringProcess ≡ constr:PlannedProcess ⊓ ∃ bfo:has_occurrent_part .constr:MeasurementProcess ⊓ ∃ bfo:occurrent_part_of .constr:PlannedProcess ⊓ ∃ constr:prescribedBy .constr:MonitoringPlan
EquivalentTo: constr:PlannedProcess and bfo:has_occurrent_part some constr:MeasurementProcess and bfo:occurrent_part_of some constr:PlannedProcess and constr:prescribedBy some constr:MonitoringPlan
SubClassOf: constr:PlannedProcess