sampling process

IRI: https://spec.industrialontologies.org/ontology/construct/SamplingProcess

Defined In: https://spec.industrialontologies.org/ontology/biopharma/MonitoringAndControl/

SubClass Of: planned process

Class Hierarchy

owl:Thing › bfo:entity › bfo:occurrent › bfo:process › planned process › sampling process

Definition

planned process of selecting and collecting a limited amount or number of some material entity in a manner which ensures it is representative of the input material entity

Explanatory Notes

sampling might involve conditioning (e.g., cooling, filtering, putting in a specific container), preparing, and documenting the sample The sampling process is designed to ensure that the test results subsequently conducted on the sample are reliable and representative of the overall material or product, supporting effective quality control and decision-making.

Examples

• Sampling process in which a technician disinfects the sampling port of a 2000 L CHO cell culture bioreactor with 70% ethanol, withdraws 15 mL of culture using a sterile syringe, discards the first 2 mL, collects the remaining 10 mL into a labeled sterile vial, and seals it for downstream analysis; Sampling process in which an operator manually collects 5 tablets from the compression chute using a stainless-steel scoop, places them into a labeled clean glass container, records the batch number and time, and seals the container for later analysis

Counter-Examples

• A technician places a labeled sample vial in a cold box and transports it to the analytical lab (this is sample transport and not sampling itself); An operator fills final product into vials for distribution; A lab analyst measures glucose concentration in a sample using a Nova BioProfile® FLEX analyzer (this is an analysis conducted after the sampling and not the sampling itself)

Synonyms

• material sampling process

Adapted From

• https://www.sciencedirect.com/topics/engineering/sampling-process

Primitive Class

This class is declared primitive and it does not have necessary and sufficient condiftions defined.

Primitive Rationale

There are insufficient constructs to create a set of necessary and sufficient conditions. In particular, pattern and all the constructs for representing that the sample is taken in a manner which ensures it is representative of the input are missing

Formal Axioms

First-Order Logic Axioms

SamplingProcess(x) → PlannedProcess(x) ∧ ∃m(MaterialEntity(m) ∧ hasInput(x, m)) ∧ ∃s((MaterialEntity(s) ∧ (memberPartOfAtSomeTime(s, m) ∨ properContinuantPartOfAtSomeTime(s, m))) ∧ hasSpecifiedOutput(x, s)) ∧ ∃p(SamplePlan(p) ∧ prescribedBy(x,p))

Semi-Formal Natural Language Axioms

if x is a ‘sampling process’, then x is a ‘planned process’ that ‘has input’ some ‘material entity’ m and that is ‘prescribed by’ some ‘sampling plan’ p and ‘has specified output’ some s, where s is either a ‘member part of at some time’ or a ‘proper continuant part of at some time’ of m

Description Logic

constr:SamplingProcess ⊑ constr:PlannedProcess

constr:SamplingProcess ⊑ ∃ constr:hasInput .bfo:material_entity

constr:SamplingProcess ⊑ ∃ constr:hasSpecifiedOutput .(∃ bfo:member_part_of_at_some_time .bfo:material_entity ⊔ ∃ bfo:proper_continuant_part_of_at_some_time .bfo:material_entity)

constr:SamplingProcess ⊑ ∃ constr:prescribedBy .constr:SamplePlan

SubClassOf: constr:PlannedProcess

SubClassOf: constr:hasInput some bfo:material_entity

SubClassOf: constr:hasSpecifiedOutput some (bfo:member_part_of_at_some_time some bfo:material_entity or bfo:proper_continuant_part_of_at_some_time some bfo:material_entity)

SubClassOf: constr:prescribedBy some constr:SamplePlan