transfection process
IRI: https://spec.industrialontologies.org/ontology/construct/TransfectionProcess
Defined In: https://spec.industrialontologies.org/ontology/biopharma/ManufacturingExecution/
SubClass Of: genetic transformation process
Class Hierarchy
owl:Thing › bfo:entity › bfo:occurrent › bfo:process › planned process › genetic transformation process › transfection process
Definition
genetic transformation process of introducing DNA or RNA into eukaryotic cells by non-viral methods to modify the cell’s genetic material
Explanatory Notes
Such introductions of foreign nucleic acid using various chemical, biological, or physical methods can result in a change of the properties of the cell, allowing the study of gene function and protein expression in the context of the cell.
Examples
- transfection of a mammalian cell by electroporation, sonoporation or microinjection
Counter-Examples
- introducing a gene encoding a recombinant protein into a yeast cell by using a virus
Adapted From
- https://www.thermofisher.com/de/de/home/references/gibco-cell-culture-basics/transfection-basics/introduction-to-transfection.html
Primitive Class
This class is declared primitive and it does not have necessary and sufficient condiftions defined.
Primitive Rationale
Insufficient constructs are present to create a set of necessary and sufficient conditions
Formal Axioms
First-Order Logic Axioms
TransfectionProcess(x) → GeneticTransformationProcess(x)
Semi-Formal Natural Language Axioms
if x is a ‘transfection process’ then x is a ‘genetic transformation process’