mobile phase role
IRI: https://spec.industrialontologies.org/ontology/construct/MobilePhaseRole
Defined In: https://spec.industrialontologies.org/ontology/biopharma/Equipment/
SubClass Of: bfo:role
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › bfo:specifically dependent continuant › bfo:realizable entity › bfo:role › mobile phase role
Definition
role held by a fluid when it is planned to be or is used in a chromatography process to percolate through or along the stationary phase
Explanatory Notes
In gas chromatography the expression carrier gas may be used for the mobile phase. In elution process the expression ‘eluent’ ‘is also used for the mobile phase.
Examples
- Water as mobile phase in reverse-phase chromatography; acetonitrile used as mobile phase in HPLC; phosphate buffer as mobile phase in ion-exchange chromatography; methanol serving as mobile phase in normal-phase chromatography; gradient of water and acetonitrile as mobile phase in gradient elution; sodium chloride solution as mobile phase in size-exclusion chromatography
Adapted From
- AFO_/role#AFRL:0000011 and GE Protein Purification Handbook and https://goldbook.iupac.org/terms/view/M03952
Primitive Class
This class is declared primitive and it does not have necessary and sufficient condiftions defined.
Primitive Rationale
There are insufficient constructs to create necessary and sufficient conditions. In particular modeling of fluid is required.
Formal Axioms
First-Order Logic Axioms
MobilePhaseRole(x) → Role(x) ∧ ∃y(MaterialEntity(y) ∧ roleOf(x, y))
Semi-Formal Natural Language Axioms
if x is a ‘mobile phase role’ then x is a ‘role’ and x is the ‘role of’ some ‘material entity’
Description Logic
constr:MobilePhaseRole ⊑ bfo:role
constr:MobilePhaseRole ⊑ ∃ constr:roleOf .bfo:material_entity
SubClassOf: bfo:role
SubClassOf: constr:roleOf some bfo:material_entity
constr:MobilePhaseRole DisjointWith: constr:StationaryPhaseRole