stationary phase

IRI: https://spec.industrialontologies.org/ontology/construct/StationaryPhase

Defined In: https://spec.industrialontologies.org/ontology/biopharma/Equipment/

SubClass Of: bfo:material entity

Class Hierarchy

owl:Thing › bfo:entity › bfo:continuant › bfo:independent continuant › bfo:material entity › stationary phase

Definition

material entity with a stationary phase role

Semi-Formal Definition:

every instance of ‘stationary phase’ is defined as exactly an instance of ‘material entity’ that ‘has role’ some ‘stationary phase role’

Explanatory Notes

Common terms such as “chromatographic bed” or “sorbent” may refer to its various physical forms. To avoid ambiguity, expressions like “liquid stationary phase” or “solid stationary phase” are preferred when specifying its physical state.

Examples

• Silica gel as stationary phase in normal-phase chromatography; C18 bonded silica as stationary phase in reverse-phase chromatography; agarose bead gel as stationary phase in size-exclusion chromatography; ion-exchange resin as stationary phase in ion-exchange chromatography; protein A immobilized on resin as stationary phase in affinity chromatography; polymeric resin as stationary phase in hydrophobic interaction chromatography.

Counter-Examples

• an unpacked chromatography column; chromatography medium when it is offered for sale by its manufacturer

Formal Axioms

First-Order Logic Definition

StationaryPhase(x) ↔ MaterialEntity(x) ∧ ∃r(StationaryPhaseRole(r) ∧ hasRole(x, r))

Description Logic

constr:StationaryPhase ≡ bfo:material_entity ⊓ ∃ constr:hasRole .constr:StationaryPhaseRole

constr:StationaryPhase ⊑ bfo:material_entity

EquivalentTo: bfo:material_entity and constr:hasRole some constr:StationaryPhaseRole

SubClassOf: bfo:material_entity