acid-base indicator role
IRI: https://spec.industrialontologies.org/ontology/construct/AcidBaseIndicatorRole
Defined In: https://spec.industrialontologies.org/ontology/biopharma/MolecularEntity/
SubClass Of: molecular color indicator role
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › bfo:specifically dependent continuant › bfo:realizable entity › bfo:role › molecular entity role › molecular indicator role › molecular visual indicator role › molecular color indicator role › acid-base indicator role
Definition
molecular color indicator role held by a molecular entity when it is used or planned to be used so that its color indicates the pH range of a material entity
Explanatory Notes
Acid-base indicators are typically weak acids or weak bases whose conjugate forms differ in color over a characteristic pH transition range. In titration applications, the indicator is selected so that its color change occurs at or near the equivalence point. In cell culture or process contexts, an acid-base indicator may be used to provide a visual indication that the medium, buffer, or solution has shifted into a different pH range.
Examples
- Phenol red bearing an acid-base indicator role when its color indicates the pH range of cell culture medium; Bromothymol blue bearing an acid-base indicator role when its color change indicates a shift from acidic to neutral or basic pH; Methyl orange bearing an acid-base indicator role during an acid-base titration; Phenolphthalein bearing an acid-base indicator role when its color change indicates the endpoint of a titration.
Adapted From
- http://purl.obolibrary.org/obo/CHEBI_50407
Primitive Class
This class is declared primitive and it does not have necessary and sufficient condiftions defined.
Primitive Rationale
There are insufficient constructs present to create a set of necessary and sufficient conditions
Formal Axioms
First-Order Logic Axioms
AcidBaseIndicatorRole(x) → MolecularColorIndicatorRole(x)
Semi-Formal Natural Language Axioms
if x is an ‘acid-base indicator role’ then x is a ‘molecular color indicator role’