cell culture holding capability
IRI: https://spec.industrialontologies.org/ontology/construct/CellCultureHoldingCapability
Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaEquipment/
SubClass Of: material containment capability
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › bfo:specifically dependent continuant › bfo:realizable entity › bfo:disposition › capability › material containment capability › cell culture holding capability
Direct subclasses:
Definition
material containment capability to contain material undergoing a cell cultivation process
Explanatory Notes
1) This capability is specific to containing material while that material undergoes a cell cultivation process, rather than holding material in general. The cultivated material may include suspension or adherent cultures, microbial cultures, cell aggregates, tissues or other multicellular structures, culture-support materials, and culture medium. 2) The capability applies to vessels and vessel-like artifacts such as T-flasks, shake flasks, spinner flasks, culture bags, microplate wells, and bioreactor vessels. 3) It does not by itself imply temperature control, carbon-dioxide control, humidity control, agitation, aeration, sterility, or aseptic operation; those should be represented by separate capabilities where needed.
Examples
- Capability of a T-flask to contain an adherent mammalian cell culture during incubation; Capability of a shake flask to contain a microbial or mammalian suspension culture during shaking cultivation; Capability of a spinner flask to contain a suspension cell culture during stirred cultivation; Capability of a cell culture bag to contain cells and medium during expansion; Capability of a bioreactor vessel to contain a cell culture during a controlled cultivation process;
Primitive Class
This class is declared primitive and it does not have necessary and sufficient condiftions defined.
Primitive Rationale
The formalization of this term requires the processes that are in the manufacturing execution and material module
Formal Axioms
First-Order Logic Axioms
CellCultureHoldingCapability(x) → MaterialContainmentCapability(x)
Semi-Formal Natural Language Axioms
if x is a ‘cell culture holding capability’ then x is a ‘material containment capability’