🟢 Biopharma Equipment Ontology

Maturity: 🟢 Released

IRI: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaEquipment/

This module contains terms and relations enabling representation of equipment types, properties (qualities, capabilities, and functions), equipment specifications and validation (e.g., methods, testing, reporting, etc.).

Annotations

Contributor

Adlane Rebai, Millipore Sigma
Ana Nikolov, OAGi
Boonserm Kulvatunyou, NIST
Cameron Gibbs, CrownPoint Technologies, LLC
Gabriela Henning, NIST
Jan Kemper, AstraZeneca
Marie-Aude Coutouly, Millipore Sigma
Melissa Weller, CrownPoint Technologies, LLC
Milos Drobnjakovic, OAGi
Stephen J. Granite, CrownPoint Technologies, LLC
Stephen Kahmann, CrownPoint Technologies, LLC

Copyright

Creator

NIIMBL BD-1 Ontology Group

License

http://opensource.org/licenses/MIT

Title

NIIMBL Equipment Ontology

Classes (71)

Class	Definition
adherent cell culture holding capability	cell culture holding capability to contain an adherent cell culture during a cell cultivation process
adherent cell culture holding function	adherent cell culture holding capability that is a function of a material entity
aeration capability	gas transfer capability to enable introduction of oxygen-containing gas to a material entity or site
affinity chromatography medium	chromatography medium which has an immobilized ligand as its part which has reversible binding capability to a specific part of a …
agitation rate controlling capability	control capability to carry out control of agitation rate
analytical chromatography system	chromatography system designed to be used in chromatography processes with the primary objective of identifying or quantifying che…
anion exchange chromatography medium	chromatography medium consisting of a matrix and positively charged molecules that are chemically bound to it
aseptic barrier capability	capability of a material artifact or engineered system to prevent or limit transfer of contaminating material across a physical bo…
bioproduction environment capability	cultivation environment capability to provide a controlled environment in which biological entities generate, or are expanded as, …
bioreactor	engineered system designed to provide a controlled environment for the cultivation of cells, tissues, or microorganisms, or for th…
bioreactor vessel	container designed to contain material undergoing a cell cultivation process and to incorporate or interface with one or more comp…
cation exchange chromatography medium	chromatography medium consisting of a matrix and negatively charged molecules that are chemically bound to it
cell culture holding capability	material containment capability to contain material undergoing a cell cultivation process
cell culture holding function	cell culture holding capability that is a function of a material entity
centrifuge	engineered system designed to separate materials by subjecting them to centrifugal acceleration generated by rotation
chromatography column	material artifact that is a tube or a cylinder designed to house chromatography medium as the stationary phase during one or more …
chromatography medium	material entity designed to selectively and reversibly retain different molecules during one or more chromatography processes
chromatography system	engineered system designed to control the fluid flow of the mobile phase, provide monitoring or detection capabilities, and house …
control capability	capability of a material artifact, agent, or engineered system to carry out control during a planned process
cryovial	vial designed for storage of material at ultra-low temperatures
cultivation environment capability	capability of an engineered system to provide a controlled environment suitable for the growth or maintenance of cells, tissues, o…
cultivation environment function	cultivation environment capability that is a function of an engineered system
depth filter	filter that does not rely on a uniform, defined pore size and that is designed to retain particles both on its surface and within …
dissolved oxygen controlling capability	control capability to carry out control of dissolved oxygen concentration within a particular liquid
exhaust gas removal capability	gas transfer capability to enable removal of gas from a material entity or site
filter	material artifact that is porous and designed to retain particles above a certain size threshold when a fluid is passed through it
flask	container that has a body wider than its neck and is designed to contain material during a material transformation, separation, me…
flow rate controlling capability	control capability to carry out control of flow rate
flow rate controlling function	flow rate controlling capability that is a function of a material artifact or engineered system
fluid transfer capability	material transfer capability to enable movement of a fluid to or from a material entity or site
foam level controlling capability	control capability to carry out control of foam level
gas transfer capability	fluid transfer capability to enable movement of a gas to or from a material entity or site
heat exchange capability	capability of a material artifact or engineered system to enable transfer of thermal energy between material entities
hydrophobic chromatography medium	chromatography medium consisting of a matrix and hydrophobic molecules that are chemically bound to it
incubator	engineered system designed to maintain controlled environmental conditions within an enclosed chamber for material entities placed…
liquid transfer capability	fluid transfer capability to enable movement of a liquid to or from a material entity or site
material transfer capability	capability of an agent, material artifact, or engineered system to enable movement of material distinct from the capability bearer…
membrane filter	filter consisting of one or more flat or pleated porous layers made from polymers, that has a defined pore size enabling the remov…
mixed mode chromatography medium	chromatography medium with immobilized functional groups designed to selectively interact with molecules through multiple distinct…
mixing capability	capability of a material artifact or engineered system to combine or redistribute material contents to produce a more uniform mate…
mixing function	mixing capability that is a function of a material artifact or engineered system
mobile phase	material entity with a mobile phase role
mobile phase role	role held by a fluid when it is planned to be or is used in a chromatography process to percolate through or along the stationary …
pH controlling capability	control capability to carry out control of pH
port	site that serves as an interface through which material, energy, or information may enter or leave
preparative chromatography system	chromatography system designed to be used in chromatography processes that produce fractions for further downstream processing, su…
pressure controlling capability	control capability to carry out control of pressure
production bioreactor	bioreactor which has a production bioreactor role
production bioreactor role	equipment role held by a bioreactor when it is used or planned to be used to carry out a biomanufacturing production process
protein A chromatography medium	affinity chromatography medium which has protein A as an immobilized ligand
protein binding capability	capability of a material entity to selectively and reversibly interact with one or more protein molecules through non-covalent mol…
rocker bag	container that is a flexible bag designed for rocking or wave-motion mixing, gently agitating its contents to provide mixing and g…
seed bioreactor	bioreactor which has a seed bioreactor role
seed bioreactor role	equipment role held by a bioreactor that is involved or planned to be involved in carrying out a cell culture expansion process th…
shake flask	flask designed for cultivating biological material or conducting chemical reactions that require aeration and mixing under agitate…
shaker	engineered system designed to apply shaking motion to material entities placed on or in it
single use role	role held by a production consumable or piece of equipment that is used or planned to be used for a single defined use before bein…
size exclusion chromatography medium	chromatography medium designed to selectively and reversibly retain molecules based on differences in their size, shape, or molecu…
solid transfer capability	material transfer capability to enable movement of a solid to or from a material entity or site
spinner flask	flask designed for cultivating cells in suspension that has as part a component with a mixing function to keep the culture uniform…
stationary phase	material entity with a stationary phase role
stationary phase role	role held by a solid, gel, or liquid that is planned to be or used in a chromatography process as the immobilized material which s…
suspension cell culture holding capability	cell culture holding capability to contain a suspension cell culture during a cell cultivation process
suspension cell culture holding function	suspension cell culture holding capability that is a function of a material entity
T-flask	flask designed for cultivating adherent cells that has as part a flat growth surface for cell attachment and a narrow neck for add…
temperature controlling capability	control capability to carry out control of temperature
thawing capability	capability that an engineered system or material artifact has to provide controlled heating to raise the temperature of a material…
thawing function	thawing capability that is a function of a material artifact or engineered system
thawing system	engineered system designed to raise the temperature of a material in a controlled manner to reach a specified setpoint, typically …
vessel headspace	site within the interior of a vessel that is not occupied by the contained bulk material and is bounded by the vessel walls and, w…
vial	container that is small, sealable, and designed for holding, storing, or dispensing small quantities of material