oxidized residue
IRI: https://spec.industrialontologies.org/ontology/construct/OxidizedResidue
Defined In: https://spec.industrialontologies.org/ontology/biopharma/MolecularEntity/
SubClass Of: modified amino acid residue
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › bfo:independent continuant › bfo:material entity › chemical moiety › amino acid residue › modified amino acid residue › oxidized residue
Definition
modified amino acid residue that results from covalent changes involving loss of hydrogen atoms or addition of oxygen atoms to the residue
Examples
- Oxidized methionine residue in a monoclonal antibody; Oxidized tryptophan residue in a recombinant protein; Oxidized cysteine residue formed during protein handling or storage; Methionine sulfoxide residue formed by oxidation of a methionine residue.
Adapted From
- http://purl.obolibrary.org/obo/MOD_00675
Primitive Class
This class is declared primitive and it does not have necessary and sufficient condiftions defined.
Primitive Rationale
This term is expected to remain primitive as the detailed treatment of chemical bonds, structure and formation is outside of the current scope of IOF. Other biological and chemical ontologies should be used for these purposes
Formal Axioms
First-Order Logic Axioms
OxidizedResidue(x) → ModifiedAminoAcidResidue(x)
Semi-Formal Natural Language Axioms
if x is an ‘oxidized residue’ then x is a ‘modified amino acid residue’