reconstitutability

IRI: https://spec.industrialontologies.org/ontology/construct/Reconstitutability

Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaMaterial/

SubClass Of: capability

Class Hierarchy

owl:Thing › bfo:entity › bfo:continuant › bfo:specifically dependent continuant › bfo:realizable entity › bfo:disposition › capability › reconstitutability

Definition

capability of a dried or concentrated material entity to form a liquid mixture that satisfies specified usage requirements when combined with an appropriate solvent or diluent

Examples

• reconstitutability of a lyophilized drug product cake with sterile water for injection; the reconstitutability of powdered cell culture medium during media preparation; the reconstitutability of a granulated medium during liquid addition; the reconstitutability of a concentrated buffer after dilution; the reconstitutability of a dried excipient blend before formulation use; reconstitutability of concentrate orange juice with treated water

Primitive Class

This class is declared primitive and it does not have necessary and sufficient condiftions defined.

Primitive Rationale

There are insufficient constructs to create a set of necessary and sufficient conditions.

Formal Axioms

First-Order Logic Axioms

Reconstitutability(x) → Capability(x) ∧ ∃m (MaterialEntity(m) ∧ capabilityOf(x, m))

Semi-Formal Natural Language Axioms

if x is a ‘reconstitutability’ then x is a ‘capability’ that is the ‘capability of’ some ‘material entity’

Description Logic

constr:Reconstitutability ⊑ constr:Capability

constr:Reconstitutability ⊑ ∃ constr:capabilityOf .bfo:material_entity

SubClassOf: constr:Capability

SubClassOf: constr:capabilityOf some bfo:material_entity