material production inducer

IRI: https://spec.industrialontologies.org/ontology/construct/MaterialProductionInducer

Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaMaterial/

SubClass Of: material functional inducer

Class Hierarchy

owl:Thing › bfo:entity › bfo:continuant › bfo:independent continuant › bfo:material entity › material functional inducer › material production inducer

Definition

material entity with a material production inducer role

Semi-Formal Definition:

every instance of ‘material production inducer’ is defined as exactly an instance of ‘material functional inducer’ that ‘has role’ some ‘material production inducer role’

Explanatory Notes

See the expanded definition under the corresponding role class. The term is formalized here as a defined class by referring to its corresponding role class and exists primarily for ontological modeling and implementation convenience.

Examples

• Tetracycline is a production inducer when added to a mammalian cell culture to activate a Tet-regulated promoter driving recombinant protein expression.

Adapted From

• https://pmc.ncbi.nlm.nih.gov/articles/PMC8015268/pdf/nihms-1685084.pdf and https://microbialcellfactories.biomedcentral.com/articles/10.1186/s12934-024-02523-w

Formal Axioms

First-Order Logic Definition

MaterialProductionInducer(x) ↔ MaterialFunctionalInducer(x) ∧ ∃r(MaterialProductionInducerRole(r) ∧ hasRole(x, r))

Description Logic

constr:MaterialProductionInducer ≡ constr:MaterialFunctionalInducer ⊓ ∃ constr:hasRole .constr:MaterialProductionInducerRole

constr:MaterialProductionInducer ⊑ constr:MaterialFunctionalInducer

EquivalentTo: constr:MaterialFunctionalInducer and constr:hasRole some constr:MaterialProductionInducerRole

SubClassOf: constr:MaterialFunctionalInducer