preparative chromatography system
IRI: https://spec.industrialontologies.org/ontology/construct/PreparativeChromatographySystem
Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaEquipment/
SubClass Of: chromatography system
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › bfo:independent continuant › bfo:material entity › bfo:object aggregate › system › engineered system › chromatography system › preparative chromatography system
Definition
chromatography system designed to be used in chromatography processes that produce fractions for further downstream processing, such as purification, formulation, or additional separations
Explanatory Notes
1) Preparative chromatography systems are commonly used for purification of target components, but can also be employed for fractionation or other separation purposes where multiple fractions may be collected and retained for further processing. 2) Preparative chromatography systems typically involve larger sample loads and scales than analytical chromatography systems, which primarily focus on identification and quantification.
Examples
- Stainless steel preparative HPLC system with large-diameter column; single-use preparative chromatography skid for monoclonal antibody purification; pilot-scale preparative ion-exchange chromatography system; large-scale preparative size-exclusion chromatography system with automated fraction collection; preparative affinity chromatography system with protein A resin; expanded bed adsorption chromatography system for feedstock clarification
Synonyms
- preparative chromatographic system
- process chromatography system
Adapted From
- https://www.cytivalifesciences.com/en/us/shop/chromatography/chromatography-systems/akta-process-chromatography-system-p-25741?psmenu=1&faq=
Primitive Class
This class is declared primitive and it does not have necessary and sufficient condiftions defined.
Primitive Rationale
There are insufficient constructs in the ontology to create necessary and sufficient conditions.
Formal Axioms
First-Order Logic Axioms
PreparativeChromatographySystem(x) → ChromatographySystem(x)
Semi-Formal Natural Language Axioms
if x is a ‘preparative chromatography system’ then x is a ‘chromatography system’