nutrient role

IRI: https://spec.industrialontologies.org/ontology/construct/NutrientRole

Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaMaterial/

SubClass Of: bfo:role

Class Hierarchy

owl:Thing › bfo:entity › bfo:continuant › bfo:specifically dependent continuant › bfo:realizable entity › bfo:role › nutrient role

Direct subclasses:

• carbon source role
• energy substrate role
• nitrogen source role

Definition

role held by a material entity that is made available to an organism or cell to support metabolism, growth, maintenance, or biomass formation by providing energy for cellular activities or to build or maintain cellular material

Explanatory Notes

This role applies to material entities that are available to an organism or cell from an external material source, such as culture medium, feed material, supplement material, food material, or another surrounding material. It is intended to distinguish externally supplied nutritive material from material synthesized internally by the organism or cell. Materials bearing this role may support catabolic processes by providing energy for cellular activities, support anabolic processes by providing material used in biosynthesis, repair, maintenance, or biomass formation, or do both.

Examples

• nutrient role borne by glucose serving as a carbon source and energy source in mammalian cell culture medium; nutrient role borne by ammonium ion serving as a nitrogen source in microbial fermentation medium; nutrient role borne by glutamine serving as a nitrogen source and energy-relevant nutrient in cell culture medium; nutrient role borne by yeast extract serving as a nutrient material in microbial culture medium; nutrient role borne by protein hydrolysate serving as a nutrient material in cell culture medium; nutrient role borne by chemically defined feed material serving as a nutrient source during fed-batch cultivation

Adapted From

• http://purl.obolibrary.org/obo/CHEBI_33284

Primitive Class

This class is declared primitive and it does not have necessary and sufficient condiftions defined.

Primitive Rationale

This term is expected to remain primitive as the detailed treatment of biochemical processes is outside of the current scope of IOF. Other biological and chemical ontologies should be used for these purposes

Formal Axioms

First-Order Logic Axioms

NutrientRole(x) → Role(x) ∧ ∃m (MaterialEntity(m) ∧ roleOf(x, m))

Semi-Formal Natural Language Axioms

if x is a ‘nutrient role’ then x is a ‘role’ that is the ‘role of’ some ‘material entity’

Description Logic

constr:NutrientRole ⊑ bfo:role

constr:NutrientRole ⊑ ∃ constr:roleOf .bfo:material_entity

SubClassOf: bfo:role

SubClassOf: constr:roleOf some bfo:material_entity