centrifugation process
IRI: https://spec.industrialontologies.org/ontology/construct/CentrifugationProcess
Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaManufacturingExecution/
SubClass Of: planned process
Class Hierarchy
owl:Thing › bfo:entity › bfo:occurrent › bfo:process › planned process › centrifugation process
Definition
planned process in which particles such as cells, organelles, or molecules are separated based on size or density by applying centrifugal forces generated by a spinning rotor
Examples
- Latex is concentrated by centrifugation to separate rubber particles from field latex; Centrifugation is used to harvest CHO cells by separating them from spent culture media after production; Spinning blood samples to separate plasma for diagnostic testing; Centrifuging cell lysates to remove debris before protein quantification;
Adapted From
- OBI:0302886
Primitive Class
This class is declared primitive and it does not have necessary and sufficient condiftions defined.
Primitive Rationale
Insufficient constructs are present to create a set of necessary and sufficient conditions
Formal Axioms
First-Order Logic Axioms
CentrifugationProcess(x) → PlannedProcess(x) ∧ ∃c(Centrifuge(c) ∧ hasParticipantAtSomeTime(x,c))
Semi-Formal Natural Language Axioms
if x is a ‘centrifugation process’ then x is a ‘planned process’ that ‘has participant at some time’ some ‘centrifuge’
Description Logic
constr:CentrifugationProcess ⊑ constr:PlannedProcess
constr:CentrifugationProcess ⊑ ∃ bfo:has_participant_at_some_time .constr:Centrifuge
SubClassOf: constr:PlannedProcess
SubClassOf: bfo:has_participant_at_some_time some constr:Centrifuge