ultrafiltration process
IRI: https://spec.industrialontologies.org/ontology/construct/UltrafiltrationProcess
Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaManufacturingExecution/
SubClass Of: membrane filtration process
Class Hierarchy
owl:Thing βΊ bfo:entity βΊ bfo:occurrent βΊ bfo:process βΊ planned process βΊ filtration process βΊ membrane filtration process βΊ ultrafiltration process
Definition
filtration process in which a membrane filter that is used has pore size in the range of 0.01 to 0.1 ΞΌm
Explanatory Notes
1) Ultrafiltration (UF) is a variety of membrane filtration in which forces such as pressure or concentration gradients lead to a separation through a semipermeable membrane. Suspended solids and solutes of high molecular weight are retained in the so-called retentate, while water and low molecular weight solutes pass through the membrane in the permeate (filtrate). 2) The stated pore-size values indicate the characteristic scale associated with ultrafiltration and are not intended to establish exact lower or upper classification boundaries. A membrane filtration process may still be classified as an ultrafiltration process when the nominal pore-size rating lies near or modestly outside this interval, provided that the membrane and its retention performance are recognized as ultrafiltration.
Examples
- Ultrafiltration is used in cheese making to concentrate casein and whey proteins while removing water, lactose, and soluble components; In mAb production, ultrafiltration concentrates antibody solutions before formulation; Ultrafiltration is applied to remove host cell proteins and as part of buffer exchange before viral filtration
Primitive Class
This class is declared primitive and it does not have necessary and sufficient condiftions defined.
Primitive Rationale
Insufficient constructs are present to create a set of necessary and sufficient conditions
Formal Axioms
First-Order Logic Axioms
UltrafiltrationProcess(x) β MembraneFiltrationProcess(x)
Semi-Formal Natural Language Axioms
if x is an βultrafiltration processβ then x is a βmembrane filtration processβ