foamability
IRI: https://spec.industrialontologies.org/ontology/construct/Foamability
Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaMaterial/
SubClass Of: capability
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › bfo:specifically dependent continuant › bfo:realizable entity › bfo:disposition › capability › foamability
Definition
capability of a liquid to form foam during a particular process
Explanatory Notes
Foamability is realized when process conditions that promote foam formation occur, for example agitation, mixing, pumping, spraying, or gas introduction. Hence, foamability should be assessed under specified process operating conditions, because the realized amount of foam depends on both mixture composition and the process conditions.
Examples
- the foamability of a cell culture medium during bioreactor sparging; the foamability of a fermentation broth during agitation; the foamability of a protein formulation during pumping or filling; the foamability of a buffer containing surfactant during mixing; the foamability of a harvest fluid during transfer
Adapted From
- https://www.sciencedirect.com/science/article/abs/pii/S0001868619303021 and https://link.springer.com/article/10.1007/s43938-023-00039-0
Primitive Class
This class is declared primitive and it does not have necessary and sufficient condiftions defined.
Primitive Rationale
There are insufficient constructs to create a set of necessary and sufficient conditions.
Formal Axioms
First-Order Logic Axioms
Foamability(x) → Capability(x) ∧ ∃m∃s (MaterialEntity(m) ∧ capabilityOf(x, m) ∧ LiquidAggregateState(s) ∧ hasQuality(m, s))
Semi-Formal Natural Language Axioms
if x is a ‘foamability’ then x is a ‘capability’ that is the ‘capability of’ some ‘material entity’ that ‘has quality’ some ‘liquid aggregate state’
Description Logic
constr:Foamability ⊑ constr:Capability
constr:Foamability ⊑ ∃ constr:capabilityOf .(bfo:material_entity ⊓ ∃ constr:hasQuality .constr:LiquidAggregateState)
SubClassOf: constr:Capability
SubClassOf: constr:capabilityOf some (bfo:material_entity and constr:hasQuality some constr:LiquidAggregateState)