osmolality
IRI: https://spec.industrialontologies.org/ontology/construct/Osmolality
Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaMaterial/
SubClass Of: bfo:relational quality
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › bfo:specifically dependent continuant › bfo:quality › bfo:relational quality › osmolality
Definition
relational quality of a solution that is the amount of osmotically active solute entities in that solution per unit mass of solvent
Examples
- the osmolality of a cell culture medium after concentrated feed addition; the osmolality of a buffer solution after salt addition; the osmolality of a liquid drug product formulation adjusted using excipients; the osmolality of spent culture medium after metabolite accumulation;
Adapted From
- http://purl.obolibrary.org/obo/PATO_0002027 and https://www.ncbi.nlm.nih.gov/sites/books/NBK567764/
Primitive Class
This class is declared primitive and it does not have necessary and sufficient condiftions defined.
Primitive Rationale
There are insufficient constructs for creating a set of necessary and sufficient conditions
Formal Axioms
First-Order Logic Axioms
Osmolality(x) → RelationalQuality(x) ∧ ∃s (Solution(s) ∧ qualityOf(x, s))
Semi-Formal Natural Language Axioms
if x is an ‘osmolality’ then x is a ‘relational quality’ that is the ‘quality of’ some ‘solution’
Description Logic
constr:Osmolality ⊑ bfo:relational_quality
constr:Osmolality ⊑ ∃ constr:qualityOf .constr:Solution
constr:Osmolality ⊓ constr:Osmolarity ⊑ ⊥
constr:Osmolality ⊓ constr:PH ⊑ ⊥
SubClassOf: bfo:relational_quality
SubClassOf: constr:qualityOf some constr:Solution
constr:Osmolality DisjointWith: (constr:Osmolarity, constr:PH, constr:Pressure)