corner point
IRI: https://spec.industrialontologies.org/ontology/construct/CornerPoint
Defined In: https://spec.industrialontologies.org/ontology/biopharma/DesignOfExperiments/
SubClass Of: design point
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › bfo:generically dependent continuant › information content entity › design point › corner point
Definition
design point located at a vertex of the region defined by the studied factor levels
Explanatory Notes
In a factorial design, corner points are the design points at the vertices of the factorial region. At each corner point, every factor is set at either its low or high factorial level. These points provide the principal contrasts for estimating main effects and interactions and delimit the factorial region represented by the selected low and high levels.
Examples
- Three-factor factorial design investigates agitation speed (low = 100 rpm, high = 200 rpm), feed rate (low = 2 mL/min, high = 6 mL/min), and temperature (low = 35 °C, high = 37 °C). The eight unique combinations of these levels constitute the factorial corner points
Adapted From
- https://wolfson.huji.ac.il/purification/PDF/Others/GE_DOE_in_Protein_Production_and_Purification_Handbook.pdf
Primitive Class
This class is declared primitive and it does not have necessary and sufficient condiftions defined.
Primitive Rationale
There are insufficient constructs to define a set of necessary and sufficient conditions.
Formal Axioms
First-Order Logic Axioms
CornerPoint(x) → DesignPoint(x)
Semi-Formal Natural Language Axioms
if x is a ‘corner point’ then x is a ‘design point’
Description Logic
SubClassOf: constr:DesignPoint