intact molecular mass
IRI: https://spec.industrialontologies.org/ontology/construct/IntactMolecularMass
Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaMaterial/
SubClass Of: molecular mass
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › bfo:specifically dependent continuant › bfo:quality › mass › molecular mass › intact molecular mass
Definition
molecular mass of a molecular entity or molecular entity population considered in its whole, intact form, without fragmentation, cleavage, or removal of any covalently bound parts
Examples
- the intact molecular mass of a monoclonal antibody of approximately 150 kDa; the intact molecular mass of an antibody-drug conjugate including its conjugated drug-linker species; the intact molecular mass of a glycosylated protein including its glycan forms;
Synonyms
- intact molecular weight
Adapted From
- https://www.fda.gov/media/182387/download
Primitive Class
This class is declared primitive and it does not have necessary and sufficient condiftions defined.
Primitive Rationale
There are insufficient constructs to define necessary and sufficient conditions.
Formal Axioms
First-Order Logic Axioms
IntactMolecularMass(x) → MolecularMass(x)
Semi-Formal Natural Language Axioms
if x is an ‘intact molecular mass’ then x is a ‘molecular mass’