antioxidant role

IRI: https://spec.industrialontologies.org/ontology/construct/AntioxidantRole

Defined In: https://spec.industrialontologies.org/ontology/biopharma/MolecularEntity/

SubClass Of: molecular entity role

Class Hierarchy

owl:Thing › bfo:entity › bfo:continuant › bfo:specifically dependent continuant › bfo:realizable entity › bfo:role › molecular entity role › antioxidant role

Definition

role held by a molecular entity when it is used or planned to be used to counteract oxidation or inhibit reactions initiated by dioxygen molecule, peroxides, or other oxidizing species

Explanatory Notes

Some molecules have antioxidant activity because of their chemical structure. In manufacturing contexts, this role is typically asserted when that activity is intentionally used, for example when a compound is added to a medium, buffer, or formulation to protect materials, nutrients, or products from oxidation during processing or storage. Antioxidant agents may be used to maintain the stability of media components, extend product shelf life, or prevent loss of potency during storage. The role may be realized through mechanisms such as scavenging reactive oxygen species, reducing oxidized molecules, chelating pro-oxidant metal ions, or inhibiting reactions initiated by dioxygen molecule or peroxides.

Examples

role held by ascorbic acid (vitamin C) added to media or formulations to prevent oxidation of sensitive components; role held by α-Tocopherol (vitamin E) used to inhibit lipid peroxidation and maintain stability of cell culture supplements or product formulations

Adapted From

http://purl.obolibrary.org/obo/CHEBI_22586

Primitive Class

This class is declared primitive and it does not have necessary and sufficient condiftions defined.

Primitive Rationale

There are insufficient constructs to create a set of necessary and sufficient conditions

Formal Axioms

First-Order Logic Axioms

AntioxidantRole(x) → MolecularEntityRole(x)

Semi-Formal Natural Language Axioms

if x is an ‘antioxidant role’ then x is a ‘molecular entity role’

Description Logic

constr:AntioxidantRole ⊑ constr:MolecularEntityRole

SubClassOf: constr:MolecularEntityRole