glycoconjugated residue
IRI: https://spec.industrialontologies.org/ontology/construct/GlycoconjugatedResidue
Defined In: https://spec.industrialontologies.org/ontology/biopharma/MolecularEntity/
SubClass Of: modified amino acid residue
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › bfo:independent continuant › bfo:material entity › chemical moiety › amino acid residue › modified amino acid residue › glycoconjugated residue
Direct subclasses:
Definition
modified amino acid residue that has a covalently attached carbohydrate or carbohydrate-derived group, formed either through enzymatic glycosidic bond formation or through non-enzymatic glycation involving a Schiff-base or Amadori-type ketosamine adduct
Examples
- N-glycosylated asparagine residue in a monoclonal antibody; O-glycosylated serine residue in a glycoprotein; O-glycosylated threonine residue in a mucin-like domain; Glycated lysine residue in a protein; Amadori-modified lysine residue formed by non-enzymatic glycation.
Adapted From
- http://purl.obolibrary.org/obo/MOD_00764
Primitive Class
This class is declared primitive and it does not have necessary and sufficient condiftions defined.
Primitive Rationale
This term is expected to remain primitive as the detailed treatment of chemical bonds, structure and formation is outside of the current scope of IOF. Other biological and chemical ontologies should be used for these purposes
Formal Axioms
First-Order Logic Axioms
GlycoconjugatedResidue(x) → ModifiedAminoAcidResidue(x)
Semi-Formal Natural Language Axioms
if x is a ‘glycoconjugated residue’ then x is a ‘modified amino acid residue’