material addition process

IRI: https://spec.industrialontologies.org/ontology/construct/MaterialAdditionProcess

Defined In: https://spec.industrialontologies.org/ontology/biopharma/ReferenceOntologyCandidates/

SubClass Of: planned process

Class Hierarchy

owl:Thing › bfo:entity › bfo:occurrent › bfo:process › planned process › material addition process

Direct subclasses:

• aeration process
• antifoam addition process
• culture feed addition process
• culture medium charging process
• inoculation process
• pH adjustment addition process

Definition

planned process that physically introduces a material entity into or onto a material entity or site

Explanatory Notes

1) A material addition process may occur as part of a broader planned process. Material put-away, loading, unloading, or other material handling processes may include a material addition process as a part without themselves being material addition processes. 2) In a material addition process, the material entity that is physically introduced is modeled as an input bearing transferred material role, while the material entity or site into or onto which it is introduced bears material addition target role. 3) The added entity may be bulk material, a discrete material entity, or a containerized material entity.

Examples

• addition of a concentrated glucose-amino-acid feed solution during fed-batch mammalian cell culture to replenish nutrients; addition of a wash or elution buffer during chromatography; addition of resuspended cells to fresh culture medium to initiate cultivation; addition of polypropylene glycol during microbial fermentation for foam control; sparging of air during mammalian cell culture to supply oxygen; addition of aluminum sulfate solution during water treatment prior to flocculation; addition of a phthalate plasticizer during PVC compounding; addition of an internal standard solution to a sample before chromatographic analysis

Adapted From

• http://purl.allotrope.org/ontologies/process#AFP_0003743

Primitive Class

This class is declared primitive and it does not have necessary and sufficient condiftions defined.

Primitive Rationale

There are insufficient constructs to create a set of necessary and sufficient conditions

Formal Axioms

First-Order Logic Axioms

MaterialAdditionProcess(x) → PlannedProcess(x) ∧ ∃m ∃mr (MaterialEntity(m) ∧ TransferredMaterialRole(mr) ∧ hasInput(x, m) ∧ hasRole(m, mr)) ∧ ∃t ∃tr ((Site(t) ∨ MaterialEntity(t)) ∧ MaterialAdditionTargetRole(tr) ∧ hasParticipantAtSomeTime(x, t) ∧ hasRole(t, tr))

Semi-Formal Natural Language Axioms

if x is a ‘material addition process’ then x is a ‘planned process’ that ‘has input’ some ‘material entity’ that ‘has role’ some ‘transferred material role’, and ‘has participant at some time’ some ‘site’ or ‘material entity’ that ‘has role’ some ‘material addition target role’

Description Logic

constr:MaterialAdditionProcess ⊑ constr:PlannedProcess

constr:MaterialAdditionProcess ⊑ ∃ bfo:has_participant_at_some_time .((bfo:site ⊔ bfo:material_entity) ⊓ ∃ constr:hasRole .constr:MaterialAdditionTargetRole)

constr:MaterialAdditionProcess ⊑ ∃ constr:hasInput .(bfo:material_entity ⊓ ∃ constr:hasRole .constr:TransferredMaterialRole)

SubClassOf: constr:PlannedProcess

SubClassOf: bfo:has_participant_at_some_time some ((bfo:site or bfo:material_entity) and constr:hasRole some constr:MaterialAdditionTargetRole)

SubClassOf: constr:hasInput some (bfo:material_entity and constr:hasRole some constr:TransferredMaterialRole)