antibody

IRI: https://spec.industrialontologies.org/ontology/construct/Antibody

Defined In: https://spec.industrialontologies.org/ontology/biopharma/MolecularEntity/

SubClass Of: protein

Class Hierarchy

owl:Thing › bfo:entity › bfo:continuant › bfo:independent continuant › bfo:material entity › molecular entity › organic molecular entity › protein › antibody

Direct subclasses:

• heterodimeric antibody
• homodimeric antibody

Definition

protein that has the function to selectively bind some antigen

Examples

• A monoclonal antibody that binds a therapeutic target antigen; An IgG antibody that binds a viral surface protein; A recombinant antibody that binds a cell-surface receptor; A neutralizing antibody that binds an antigen and blocks its biological activity; An antibody used as a capture reagent in an immunoassay.

Adapted From

• https://tools.thermofisher.com/content/sfs/brochures/1601975-Antibody-Production-Purification-Guide.pdf

Primitive Class

This class is declared primitive and it does not have necessary and sufficient condiftions defined.

Primitive Rationale

There are insufficient constructs to define a set of necessary and sufficient conditions.

Formal Axioms

First-Order Logic Axioms

Antibody(x) → Protein(x)

Semi-Formal Natural Language Axioms

if x is an ‘antibody’ then x is a ‘protein’

Description Logic

constr:Antibody ⊑ constr:Protein

SubClassOf: constr:Protein