glycoprotein
IRI: https://spec.industrialontologies.org/ontology/construct/Glycoprotein
Defined In: https://spec.industrialontologies.org/ontology/biopharma/MolecularEntity/
SubClass Of: protein
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › bfo:independent continuant › bfo:material entity › molecular entity › organic molecular entity › protein › glycoprotein
Definition
protein that includes at least one glycosylated residue
Semi-Formal Definition:
every instance of ‘glycoprotein’ is defined as exactly an instance of ‘protein’ that ‘has proper continuant part at all times’ some ‘glycosylated residue’
Examples
- Monoclonal antibody with an N-glycosylated asparagine residue in its Fc region; Recombinant erythropoietin containing N-glycosylated and O-glycosylated residues; Fc-fusion protein containing an N-glycosylated residue; Viral envelope protein containing glycosylated residues; Host cell glycoprotein detected as a process-related impurity.
Direct Source
- http://purl.obolibrary.org/obo/PR_000037069
Formal Axioms
First-Order Logic Definition
Glycoprotein(x) ↔ Protein(x) ∧ ∃y (hasProperContinuantPartAtAllTimes(x, y) ∧ GlycosylatedResidue(y))
Description Logic
constr:Glycoprotein ≡ constr:Protein ⊓ ∃ bfo:has_proper_continuant_part_at_all_times .constr:GlycosylatedResidue
EquivalentTo: constr:Protein and bfo:has_proper_continuant_part_at_all_times some constr:GlycosylatedResidue
SubClassOf: constr:Protein