quality attribute
IRI: https://spec.industrialontologies.org/ontology/construct/QualityAttribute
Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaParameter/
SubClass Of: bfo:specifically dependent continuant
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › bfo:specifically dependent continuant › quality attribute
Direct subclasses:
Definition
quality or capability that is prescribed by a quality attribute specification
Semi-Formal Definition:
every instance of ‘quality attribute’ is defined as exactly an instance of ‘quality’ or ‘capability’ that is ‘prescribed by’ some ‘quality attribute specification’
Explanatory Notes
See the expanded definition under the corresponding specification class. The term is formalized here as a defined class by referring to its corresponding specification class and exists primarily for ontological modeling and implementation convenience.
Examples
- content uniformity of the dosage units in a batch; level of degradation products in the formulation; residual solvent level in the final product; dissolution capability of a dosage form; moisture content of the drug product; microbial load in the final product; color of the tablet or capsule; shape of the dosage form; size of the finished unit; odor of the drug product;
Counter-Examples
- yield of the protein purification step
Formal Axioms
First-Order Logic Definition
QualityAttribute(x) ↔ (Quality(x) ∨ Capability(x)) ∧ ∃s(QualityAttributeSpecification(s) ∧ prescribedBy(x, s))
Description Logic
constr:QualityAttribute ≡ (bfo:quality ⊔ constr:Capability) ⊓ ∃ constr:prescribedBy .constr:QualityAttributeSpecification
constr:QualityAttribute ⊑ bfo:specifically_dependent_continuant
EquivalentTo: (bfo:quality or constr:Capability) and constr:prescribedBy some constr:QualityAttributeSpecification
SubClassOf: bfo:specifically_dependent_continuant