aliquoting process

IRI: https://spec.industrialontologies.org/ontology/construct/AliquotingProcess

Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaMonitoringAndControl/

SubClass Of: material sampling process

Class Hierarchy

owl:Thing › bfo:entity › bfo:occurrent › bfo:process › planned process › material sampling process › aliquoting process

Definition

material sampling process in which a homogeneous material entity is subdivided into multiple portions of defined amount, each portion representing the composition of the source

Explanatory Notes

1) Because the source material is assumed to be homogeneous, the resulting aliquots represent the whole with negligible sampling error. 2) The process produces multiple portions that can be uniquely identified, stored, or used independently

Examples

• aliquoting a well-mixed harvested cell culture fluid sample into labeled 5 mL portions for distribution across analytical laboratories; division of a well-mixed serum sample into 1 mL cryovials for quality control testing and archiving

Adapted From

• https://goldbook.iupac.org/terms/view/A00218 and http://purl.obolibrary.org/obo/NCIT_C124326

Primitive Class

This class is declared primitive and it does not have necessary and sufficient condiftions defined.

Primitive Rationale

There are insufficient constructs to create a set of necessary and sufficient conditions

Formal Axioms

First-Order Logic Axioms

AliquotingProcess(x) → MaterialSamplingProcess(x) ∧ ∃i∃h∃o1∃h1 (MaterialEntity(i) ∧ CompositionalHomogeneity(h) ∧ hasInput(x, i) ∧ hasQuality(i, h) ∧ MaterialEntity(o1) ∧ hasSpecifiedOutput(x, o1) ∧ properContinuantPartOfAtSomeTime(o1, i) ∧ CompositionalHomogeneity(h1) ∧ hasQuality(o1, h1))

Semi-Formal Natural Language Axioms

if x is an ‘aliquoting process’ then x is a ‘material sampling process’ that ‘has input’ some compositionally homogeneous ‘material entity’ i and ‘has specified output’ some ‘material entity’ that is a ‘proper continuant part of at some time’ i and ‘has quality’ some ‘compositional homogeneity’

Description Logic

constr:AliquotingProcess ⊑ constr:MaterialSamplingProcess

constr:AliquotingProcess ⊑ ∃ constr:hasInput .(bfo:material_entity ⊓ ∃ constr:hasQuality .constr:CompositionalHomogeneity)

constr:AliquotingProcess ⊑ ∃ constr:hasSpecifiedOutput .(bfo:material_entity ⊓ ∃ bfo:proper_continuant_part_of_at_some_time .(bfo:material_entity ⊓ ∃ constr:hasQuality .constr:CompositionalHomogeneity) ⊓ ∃ constr:hasQuality .constr:CompositionalHomogeneity)

SubClassOf: constr:MaterialSamplingProcess

SubClassOf: constr:hasInput some (bfo:material_entity and constr:hasQuality some constr:CompositionalHomogeneity)

SubClassOf: constr:hasSpecifiedOutput some (bfo:material_entity and bfo:proper_continuant_part_of_at_some_time some (bfo:material_entity and constr:hasQuality some constr:CompositionalHomogeneity) and constr:hasQuality some constr:CompositionalHomogeneity)