complete culture medium role
IRI: https://spec.industrialontologies.org/ontology/construct/CompleteCultureMediumRole
Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaMaterial/
SubClass Of: bfo:role
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › bfo:specifically dependent continuant › bfo:realizable entity › bfo:role › complete culture medium role
Definition
role held by a culture medium when it is used or planned for direct use in a cell culture process to meet the full set of nutritional, biological, and physicochemical requirements specified for that process without requiring prior supplementation
Explanatory Notes
A culture medium bearing this role may be supplied as a complete formulation or prepared in advance by supplementing a basal culture medium with materials such as serum or growth factors. In either case, it requires no further supplementation before direct use in the specified cell culture process. The addition of culture feeds later in the process does not alter its classification as a complete culture medium.
Examples
- DMEM (Dulbecco’s Modified Eagle’s Medium) supplemented with 10% fetal bovine serum bearing a complete culture medium role when planned for direct use in a mammalian cell culture process
Adapted From
- https://www.labome.com/method/Cell-Culture-Media-A-Review.html
Primitive Class
This class is declared primitive and it does not have necessary and sufficient condiftions defined.
Primitive Rationale
There are insufficient constructs for creating a set of necessary and sufficient conditions
Formal Axioms
First-Order Logic Axioms
CompleteCultureMediumRole(x) → Role(x) ∧ ∃m (CultureMedium(m) ∧ roleOf(x, m)) ∧ ∀p (hasRealization(x, p) → (PlannedProcess(p) ∧ ∃c (CellCulture(c) ∧ hasParticipantAtSomeTime(p, c))))
Semi-Formal Natural Language Axioms
if x is a ‘complete culture medium role’ then x is a ‘role’ that is the ‘role of’ some ‘culture medium’, and if x ‘has realization’ some entity then that entity is a ‘planned process’ that ‘has participant at some time’ some ‘cell culture’
Description Logic
constr:CompleteCultureMediumRole ⊑ bfo:role
constr:CompleteCultureMediumRole ⊑ ∀ bfo:has_realization .(constr:PlannedProcess ⊓ ∃ bfo:has_participant_at_some_time .constr:CellCulture)
constr:CompleteCultureMediumRole ⊑ ∃ constr:roleOf .constr:CultureMedium
SubClassOf: bfo:role
SubClassOf: bfo:has_realization only (constr:PlannedProcess and bfo:has_participant_at_some_time some constr:CellCulture)
SubClassOf: constr:roleOf some constr:CultureMedium