basal culture medium role

IRI: https://spec.industrialontologies.org/ontology/construct/BasalCultureMediumRole

Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaMaterial/

SubClass Of: bfo:role

Class Hierarchy

owl:Thing › bfo:entity › bfo:continuant › bfo:specifically dependent continuant › bfo:realizable entity › bfo:role › basal culture medium role

Definition

role held by a culture medium when it is used or planned to be used either directly in a cell culture process to provide essential nutritional and physicochemical support or together with supplements to prepare a complete culture medium for such a process

Examples

• MEM bearing a basal culture medium role when planned to be supplemented with fetal bovine serum to support robust proliferation of mammalian cells

Adapted From

• https://www.labome.com/method/Cell-Culture-Media-A-Review.html

Primitive Class

This class is declared primitive and it does not have necessary and sufficient condiftions defined.

Primitive Rationale

There are insufficient constructs for creating a set of necessary and sufficient conditions

Formal Axioms

First-Order Logic Axioms

BasalCultureMediumRole(x) → Role(x) ∧ ∃m (CultureMedium(m) ∧ roleOf(x, m)) ∧ ∀p (hasRealization(x, p) → (PlannedProcess(p) ∧ ((∃s (CultureMediumSupplement(s) ∧ hasInput(p, s))) ∨ (∃c (CellCulture(c) ∧ hasParticipantAtSomeTime(p, c))))))

Semi-Formal Natural Language Axioms

if x is a ‘basal culture medium role’ then x is a ‘role’ that is the ‘role of’ some ‘culture medium’, and if x ‘has realization’ some entity then that entity is a ‘planned process’ that either ‘has input’ some ‘culture medium supplement’ or ‘has participant at some time’ some ‘cell culture’

Description Logic

constr:BasalCultureMediumRole ⊑ bfo:role

constr:BasalCultureMediumRole ⊑ ∀ bfo:has_realization .((constr:PlannedProcess ⊓ ∃ bfo:has_participant_at_some_time .constr:CellCulture) ⊔ (constr:PlannedProcess ⊓ ∃ constr:hasInput .constr:CultureMediumSupplement))

constr:BasalCultureMediumRole ⊑ ∃ constr:roleOf .constr:CultureMedium

SubClassOf: bfo:role

SubClassOf: bfo:has_realization only ((constr:PlannedProcess and bfo:has_participant_at_some_time some constr:CellCulture) or (constr:PlannedProcess and constr:hasInput some constr:CultureMediumSupplement))

SubClassOf: constr:roleOf some constr:CultureMedium