culture medium supplement

IRI: https://spec.industrialontologies.org/ontology/construct/CultureMediumSupplement

Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaMaterial/

SubClass Of: bfo:material entity

Class Hierarchy

owl:Thing › bfo:entity › bfo:continuant › bfo:independent continuant › bfo:material entity › culture medium supplement

Definition

material entity that has a culture medium supplement role

Semi-Formal Definition:

every instance of ‘culture medium supplement’ is defined as exactly an instance of ‘material entity’ that ‘has role’ some ‘culture medium supplement role’

Explanatory Notes

See the expanded definition under the corresponding role class. The term is formalized here as a defined class by referring to its corresponding role class and exists primarily for ontological modeling and implementation convenience.

Examples

• Albumin solution is a media supplement when added to serum-free medium to stabilize cells; ITS+3 Liquid Media Supplement (100×), a defined mixture of insulin, human transferrin, sodium selenite, linoleic acid, oleic acid added to serum-free medium to support viability and specialized functions;

Adapted From

• https://www.labome.com/method/Cell-Culture-Media-A-Review.html and https://www.thermofisher.com/rs/en/home/life-science/cell-culture/mammalian-cell-culture/media-supplements.html

Formal Axioms

First-Order Logic Definition

CultureMediumSupplement(x) ↔ MaterialEntity(x) ∧ ∃r(CultureMediumSupplementRole(r) ∧ hasRole(x, r))

Description Logic

constr:CultureMediumSupplement ≡ bfo:material_entity ⊓ ∃ constr:hasRole .constr:CultureMediumSupplementRole

constr:CultureMediumSupplement ⊑ bfo:material_entity

EquivalentTo: bfo:material_entity and constr:hasRole some constr:CultureMediumSupplementRole

SubClassOf: bfo:material_entity