total cell density
IRI: https://spec.industrialontologies.org/ontology/construct/TotalCellDensity
Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaMaterial/
SubClass Of: cell density
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › bfo:specifically dependent continuant › bfo:quality › bfo:relational quality › density › number density › cell density › total cell density
Definition
cell density that is the total number of cells per unit size
Explanatory Notes
Total cell density accounts for both viable and non-viable cells in the assessed cell population. A cell density restricted to viable cells is represented as viable cell density.
Examples
- the total cell density of a bioreactor culture sample measured by an automated cell counter; the total cell density of a CHO cell culture during production; the total cell density of a seed train culture before inoculation;
Adapted From
- https://www.sciencedirect.com/topics/medicine-and-dentistry/cell-density and https://www.sigmaaldrich.com/US/en/technical-documents/protocol/analytical-chemistry/photometry-and-reflectometry/cell-density-measurement-by-od600-method?srsltid=AfmBOoqxMLTlROXCkIoHCGlcNFWUSSZvftakFCMkyCL5l9gpB-s7B3yL and http://purl.allotrope.org/ontologies/quality#AFQ_0000181
Primitive Class
This class is declared primitive and it does not have necessary and sufficient condiftions defined.
Primitive Rationale
There are insufficient constructs for creating a set of necessary and sufficient conditions.
Formal Axioms
First-Order Logic Axioms
TotalCellDensity(x) → CellDensity(x)
Semi-Formal Natural Language Axioms
if x is a ‘total cell density’ then x is a ‘cell density’
Description Logic
SubClassOf: constr:CellDensity