complex N-glycolylneuraminic acid containing N-glycan moiety

IRI: https://spec.industrialontologies.org/ontology/construct/ComplexNGlycolylneuraminicAcidContainingNGlycanMoiety

Defined In: https://spec.industrialontologies.org/ontology/biopharma/MolecularEntity/

SubClass Of: complex sialylated N-glycan moiety

Class Hierarchy

owl:Thing › bfo:entity › bfo:continuant › bfo:independent continuant › bfo:material entity › chemical moiety › N-glycan moiety › core pentasaccharide N-glycan moiety › biantennary complex N-glycan moiety › complex sialylated N-glycan moiety › complex N-glycolylneuraminic acid containing N-glycan moiety

Definition

complex sialylated N-glycan moiety that has as part one or more N-glycolylneuraminic acid (NGNA) residues

Semi-Formal Definition:

every instance of ‘complex N-glycolylneuraminic acid containing N-glycan moiety’ is defined as exactly an instance of ‘complex sialylated N-glycan moiety’ that ‘has proper continuant part at all times’ some ‘N-glycolylneuraminic acid residue’

Examples

• Complex sialylated N-glycan moiety containing a terminal N-glycolylneuraminic acid residue; NGNA-containing complex N-glycan moiety detected during glycan profiling of a recombinant glycoprotein; Biantennary complex N-glycan moiety with one branch terminating in an N-glycolylneuraminic acid residue.

Adapted From

• https://pmc.ncbi.nlm.nih.gov/articles/PMC4634315/

Formal Axioms

First-Order Logic Definition

ComplexNGlycolylneuraminicAcidContainingNGlycanMoiety(x) ↔ ComplexSialylatedNGlycanMoiety(x) ∧ ∃y (hasProperContinuantPartAtAllTimes(x, y) ∧ NGlycolylneuraminicAcidResidue(y))

Description Logic

constr:ComplexNGlycolylneuraminicAcidContainingNGlycanMoiety ≡ constr:ComplexSialylatedNGlycanMoiety ⊓ ∃ bfo:has_proper_continuant_part_at_all_times .constr:NGlycolylneuraminicAcidResidue

constr:ComplexNGlycolylneuraminicAcidContainingNGlycanMoiety ⊑ constr:ComplexSialylatedNGlycanMoiety

EquivalentTo: constr:ComplexSialylatedNGlycanMoiety and bfo:has_proper_continuant_part_at_all_times some constr:NGlycolylneuraminicAcidResidue

SubClassOf: constr:ComplexSialylatedNGlycanMoiety