pH adjusting agent role

IRI: https://spec.industrialontologies.org/ontology/construct/PHAdjustingAgentRole

Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaMaterial/

SubClass Of: bfo:role

Class Hierarchy

owl:Thing › bfo:entity › bfo:continuant › bfo:specifically dependent continuant › bfo:realizable entity › bfo:role › pH adjusting agent role

Direct subclasses:

• acidifying agent role
• alkalizing agent role

Definition

role of a material entity when it is used, or planned to be used to adjust pH

Explanatory Notes

The role may also be assigned to materials used with hydrated, moist, or dissolvable materials, where acid-base behavior becomes relevant during hydration, dissolution, reconstitution, or processing

Examples

• the pH adjuster role of hydrochloric acid solution during buffer preparation; the pH adjuster role of sodium hydroxide solution during formulation pH adjustment; the pH adjuster role of carbon dioxide when it is added to lower pH during a production culture process

Adapted From

• https://www.fda.gov/media/164920/download

Primitive Class

This class is declared primitive and it does not have necessary and sufficient condiftions defined.

Primitive Rationale

There are insufficient constructs to create a set of necessary and sufficient conditions

Formal Axioms

First-Order Logic Axioms

PHAdjustingAgentRole(x) → Role(x) ∧ ∃m (MaterialEntity(m) ∧ roleOf(x, m))

Semi-Formal Natural Language Axioms

if x is a ‘pH adjusting agent role’ then x is a ‘role’ that is the ‘role of’ some ‘material entity’

Description Logic

constr:PHAdjustingAgentRole ⊑ bfo:role

constr:PHAdjustingAgentRole ⊑ ∃ constr:roleOf .bfo:material_entity

SubClassOf: bfo:role

SubClassOf: constr:roleOf some bfo:material_entity