amino acid sequence
IRI: https://spec.industrialontologies.org/ontology/construct/AminoAcidSequence
Defined In: https://spec.industrialontologies.org/ontology/biopharma/MolecularEntity/
SubClass Of: biological sequence
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › bfo:generically dependent continuant › biological sequence › amino acid sequence
Definition
biological sequence that is the ordered pattern of amino-acid residues that constitute a particular continuous peptide or protein molecule
Examples
- The amino acid sequence of a monoclonal antibody heavy chain; The amino acid sequence of a monoclonal antibody light chain; The amino acid sequence of a recombinant enzyme; The amino acid sequence of a synthetic peptide; The amino acid sequence of a peptide impurity detected during product characterization
Synonyms
- peptide sequence
- primary structure sequence
Adapted From
- http://purl.obolibrary.org/obo/SO_0000104 and https://www.codamono.com/biointerchange/gfvo#PeptideSequence and https://www.ema.europa.eu/en/documents/scientific-guideline/ich-q-6-b-test-procedures-and-acceptance-criteria-biotechnologicalbiological-products-step-5_en.pdf
Primitive Class
This class is declared primitive and it does not have necessary and sufficient condiftions defined.
Primitive Rationale
There are insufficient constructs to create a set of necessary and sufficient conditions
Formal Axioms
First-Order Logic Axioms
AminoAcidSequence(x) → BiologicalSequence(x) ∧ ∀y (genericallyDependsOnAtSomeTime(x, y) → (Peptide(y) ∨ Protein(y)))
Semi-Formal Natural Language Axioms
if x is an ‘amino acid sequence’ then x is a ‘biological sequence’ and x ‘generically depends on at some time’ only on some ‘peptide’ or ‘protein’
Description Logic
constr:AminoAcidSequence ⊑ constr:BiologicalSequence
constr:AminoAcidSequence ⊑ ∀ bfo:generically_depends_on_at_some_time .(constr:Peptide ⊔ constr:Protein)
SubClassOf: constr:BiologicalSequence
SubClassOf: bfo:generically_depends_on_at_some_time only (constr:Peptide or constr:Protein)
constr:AminoAcidSequence DisjointWith: constr:NucleotideSequence