harm severity value expression
IRI: https://spec.industrialontologies.org/ontology/construct/HarmSeverityValueExpression
Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaRiskManagement/
SubClass Of: value expression
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › bfo:generically dependent continuant › information content entity › value expression › harm severity value expression
Definition
value expression that represents the magnitude of possible or actual harm
Examples
- minor patient injury; moderate bloodstream infection severity; severe hypoxic injury; severity level 2 for product damage; severity level 4 for coil and cryostat damage; severity score 3 on a 5-point scale for anaphylactic state
Adapted From
- https://www.ema.europa.eu/en/documents/scientific-guideline/international-conference-harmonisation-technical-requirements-registration-pharmaceuticals-human-use-ich-guideline-q9-quality-risk-management-step-5-first-version_en.pdf
Primitive Class
This class is declared primitive and it does not have necessary and sufficient condiftions defined.
Primitive Rationale
There are insufficient constructs to create a set of necessary and sufficient conditions
Formal Axioms
First-Order Logic Axioms
HarmSeverityValueExpression(x) → ValueExpression(x) ∧ ∃h (HarmSpecification(h) ∧ continuantPartOfAtAllTimes(x, h))
Semi-Formal Natural Language Axioms
if x is a ‘harm severity value expression’ then x is a ‘value expression’ that is ‘continuant part of at all times’ some ‘harm specification’
Description Logic
constr:HarmSeverityValueExpression ⊑ constr:ValueExpression
constr:HarmSeverityValueExpression ⊑ ∃ bfo:continuant_part_of_at_all_times .constr:HarmSpecification
SubClassOf: constr:ValueExpression
SubClassOf: bfo:continuant_part_of_at_all_times some constr:HarmSpecification