molecular messenger role
IRI: https://spec.industrialontologies.org/ontology/construct/MolecularMessengerRole
Defined In: https://spec.industrialontologies.org/ontology/biopharma/MolecularEntity/
SubClass Of: molecular entity role
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › bfo:specifically dependent continuant › bfo:realizable entity › bfo:role › molecular entity role › molecular messenger role
Direct subclasses:
Definition
role held by a molecular entity that participates in transmitting biological signals between or within cells, tissues, or organs to support coordination of biological processes
Examples
- Molecular messenger role held by insulin when added to cell culture medium to promote glucose uptake and anabolic metabolism; Molecular messenger role held by epidermal growth factor (EGF) when added to serum-free media to stimulate cell proliferation
Adapted From
- http://purl.obolibrary.org/obo/CHEBI_33280 and https://www.ncbi.nlm.nih.gov/books/NBK538154/
Primitive Class
This class is declared primitive and it does not have necessary and sufficient condiftions defined.
Primitive Rationale
This term is expected to remain primitive as the detailed treatment of molecular messaging is outside of the current scope of IOF. Other biological and chemical ontologies should be used for these purposes
Formal Axioms
First-Order Logic Axioms
MolecularMessengerRole(x) → MolecularEntityRole(x)
Semi-Formal Natural Language Axioms
if x is a ‘molecular messenger role’ then x is a ‘molecular entity role’