retention sample role

IRI: https://spec.industrialontologies.org/ontology/construct/RetentionSampleRole

Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaMonitoringAndControl/

SubClass Of: bfo:role

Class Hierarchy

owl:Thing › bfo:entity › bfo:continuant › bfo:specifically dependent continuant › bfo:realizable entity › bfo:role › retention sample role

Definition

role that is held by a material sample set aside for future testing, examination, identification, or investigation

Explanatory Notes

Commonly includes requirements on retained quantity (e.g., enough for confirmatory analyses) and on separate identification, packaging, sealing, and storage.

Examples

• the retention sample role borne by a separately identified portion of an incoming raw-material lot retained for future confirmatory analysis; the retention sample role borne by a stored culture-medium lot sample retained for future identity, quality, or investigation testing; the retention sample role borne by a finished-drug-product sample retained from a released batch for possible examination or confirmatory testing during shelf life

Adapted From

• https://www.who.int/docs/default-source/medicines/norms-and-standards/guidelines/quality-control/trs929-annex4-guidelinessamplingpharmproducts.pdf?sfvrsn=f6273f30_2

Primitive Class

This class is declared primitive and it does not have necessary and sufficient condiftions defined.

Primitive Rationale

There are insufficient constructs to create necessary and sufficient conditions.

Formal Axioms

First-Order Logic Axioms

RetentionSampleRole(x) → Role(x) ∧ ∃s (MaterialSample(s) ∧ roleOf(x, s))

Semi-Formal Natural Language Axioms

if x is a ‘retention sample role’ then x is a ‘role’ that is the ‘role of’ some ‘material sample’

Description Logic

constr:RetentionSampleRole ⊑ bfo:role

constr:RetentionSampleRole ⊑ ∃ constr:roleOf .constr:MaterialSample

SubClassOf: bfo:role

SubClassOf: constr:roleOf some constr:MaterialSample