thermal stability
IRI: https://spec.industrialontologies.org/ontology/construct/ThermalStability
Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaReferenceOntologyAttributes/
SubClass Of: stability
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › bfo:specifically dependent continuant › bfo:realizable entity › bfo:disposition › capability › stability › thermal stability
Definition
stability that is the capability of a material entity to resist change in one or more of its attributes during exposure to a particular temperature condition
Examples
- Thermal stability of a drug substance batch during refrigerated storage; Thermal stability of a protein formulation during accelerated stability testing at elevated temperature; Thermal stability of a cell culture medium lot during storage at 2–8 °C; Thermal stability of a process intermediate during a defined room-temperature hold;
Primitive Class
This class is declared primitive and it does not have necessary and sufficient condiftions defined.
Primitive Rationale
There are insufficient constructs to create a set of necessary and sufficient conditions.
Formal Axioms
First-Order Logic Axioms
ThermalStability(x) → Stability(x)
Semi-Formal Natural Language Axioms
if x is ‘thermal stability’ then x is a ‘stability’
Description Logic
SubClassOf: constr:Stability