concentration

IRI: https://spec.industrialontologies.org/ontology/construct/Concentration

Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaMaterial/

SubClass Of: bfo:relational quality

Class Hierarchy

owl:Thing › bfo:entity › bfo:continuant › bfo:specifically dependent continuant › bfo:quality › bfo:relational quality › concentration

Direct subclasses:

• mass concentration
• molar concentration
• product titer
• solution saturation concentration

Definition

relational quality of a mixture that is the amount of substance or number or mass or volume of a specified constituent of the mixture per unit volume of that mixture

Examples

• mass concentration of glucose in a cell culture medium; the molar concentration of sodium chloride in a buffer solution; the mass concentration of dissolved oxygen in culture fluid; the mass concentration of protein in a drug substance solution; the molar concentration of carbon dioxide in incubator air

Adapted From

• http://purl.obolibrary.org/obo/PATO_0000033 and https://pubs.rsc.org/ay/article/12/41/5010/673606/Units-and-quantities-for-analytical-chemistry

Primitive Class

This class is declared primitive and it does not have necessary and sufficient condiftions defined.

Primitive Rationale

There are insufficient constructs for creating a set of necessary and sufficient conditions

Formal Axioms

First-Order Logic Axioms

Concentration(x) → RelationalQuality(x) ∧ ∃m (MixedMaterial(m) ∧ qualityOf(x, m) ∧ ∀c (hasMagnitudeBasisInBearerPart(x, c) → (MaterialEntity(c) ∧ isMadeOfAtSomeTime(m, c))))

Semi-Formal Natural Language Axioms

if x is a ‘concentration’ then x is a ‘relational quality’ that is the ‘quality of’ some ‘mixed material’, and if x ‘has magnitude basis in bearer part’ some c, then c is a ‘material entity’ of which that same ‘mixed material’ ‘is made of at some time’

Description Logic

constr:Concentration ⊑ bfo:relational_quality

constr:Concentration ⊑ ∀ constr:hasMagnitudeBasisInBearerPart .(bfo:material_entity ⊓ ∃ constr:isMadeOfAtSomeTime⁻ .constr:MixedMaterial)

constr:Concentration ⊑ ∃ constr:qualityOf .constr:MixedMaterial

SubClassOf: bfo:relational_quality

SubClassOf: constr:hasMagnitudeBasisInBearerPart only (bfo:material_entity and inverse constr:isMadeOfAtSomeTime some constr:MixedMaterial)

SubClassOf: constr:qualityOf some constr:MixedMaterial