amorphous structure

IRI: https://spec.industrialontologies.org/ontology/construct/AmorphousStructure

Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaReferenceOntologyAttributes/

SubClass Of: physical structure

Class Hierarchy

owl:Thing › bfo:entity › bfo:continuant › bfo:specifically dependent continuant › bfo:quality › morphological quality › physical structure › amorphous structure

Definition

physical structure that inheres in a solid material entity by virtue of the material entity lacking the long-range order characteristic of a crystalline structure

Examples

• the amorphous structure of a lyophilized protein formulation cake; the amorphous structure of spray-dried lactose; the amorphous structure of an amorphous solid dispersion containing a poorly soluble drug substance; the amorphous structure of glass;

Adapted From

• https://en.wikipedia.org/wiki/Amorphous_solid

Primitive Class

This class is declared primitive and it does not have necessary and sufficient condiftions defined.

Primitive Rationale

There are insufficient constructs for creating a set of necessary and sufficient conditions

Formal Axioms

First-Order Logic Axioms

AmorphousStructure(x) → PhysicalStructure(x) ∧ ∃m∃s (MaterialEntity(m) ∧ qualityOf(x, m) ∧ SolidAggregateState(s) ∧ hasQuality(m, s))

Semi-Formal Natural Language Axioms

if x is an ‘amorphous structure’ then x is a ‘physical structure’ that is the ‘quality of’ some ‘material entity’ that ‘has quality’ some ‘solid aggregate state’

Description Logic

constr:AmorphousStructure ⊑ constr:PhysicalStructure

constr:AmorphousStructure ⊑ ∃ constr:qualityOf .(bfo:material_entity ⊓ ∃ constr:hasQuality .constr:SolidAggregateState)

constr:AmorphousStructure ⊓ constr:CrystallineStructure ⊑ ⊥

constr:AmorphousStructure ⊓ constr:SemiCrystallineStructure ⊑ ⊥

SubClassOf: constr:PhysicalStructure

SubClassOf: constr:qualityOf some (bfo:material_entity and constr:hasQuality some constr:SolidAggregateState)

constr:AmorphousStructure DisjointWith: (constr:CrystallineStructure, constr:SemiCrystallineStructure)