total material added
IRI: https://spec.industrialontologies.org/ontology/construct/TotalMaterialAdded
Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaParameter/
SubClass Of: process characteristic
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › process characteristic › total material added
Definition
process characteristic that is the total quantity of a particular material that is added during a particular process
Explanatory Notes
Total material added is evaluated over one or more material addition events in a planned process. The added material may be supplied in a single addition, multiple bolus additions, or continuous feeding. The quantity may be expressed as mass, volume, amount of substance, or another specified material quantity. This characteristic should be distinguished from addition rate or feed rate, which describe the rate of material addition.
Examples
- a viral inactivation process has total material added of 0.5 L acid solution from a single bolus addition for pH adjustment; a production culture process has total material added of 73 g galactose from multiple bolus additions during the production phase; a chromatography column equilibration process has total material added of 6 column volumes of equilibration buffer
Primitive Class
This class is declared primitive and it does not have necessary and sufficient condiftions defined.
Primitive Rationale
There are insufficient constructs for creating a set of necessary and sufficient conditions
Formal Axioms
First-Order Logic Axioms
TotalMaterialAdded(x) → ProcessCharacteristic(x) ∧ ∃p(PlannedProcess(p) ∧ processCharacteristicOf(x,p))
Semi-Formal Natural Language Axioms
if x is a ‘total material added’ then x is a ‘process characteristic’ that is the ‘process characteristic of’ some ‘planned process’