material aliquot
IRI: https://spec.industrialontologies.org/ontology/construct/MaterialAliquot
Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaMonitoringAndControl/
SubClass Of: material sample
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › bfo:independent continuant › bfo:material entity › material sample › material aliquot
Definition
material entity that is the specified output of some aliquoting process
Semi-Formal Definition:
every instance of ‘material aliquot’ is defined as exactly an instance of ‘material entity’ that ‘is specified output of’ some ‘aliquoting process’
Explanatory Notes
1) By assumption, aliquots are produced from a homogeneous source material, so each aliquot is considered to represent the composition of the whole with negligible sampling error. 2) In practice, aliquots are typically assigned unique identifiers (e.g., IDs, barcodes) to enable independent use and traceability. 3) In laboratory and biobanking contexts, an aliquot is typically a sub-sample taken from a primary biospecimen or analyte, prepared so that it can be distributed, stored, or analyzed independently.
Examples
- a 2 mL portion of purified protein reference material contained in one of several labeled vials prepared from the same homogeneous bulk lot;
Adapted From
- https://docs.gdc.cancer.gov/Encyclopedia/pages/Aliquot/ and https://goldbook.iupac.org/terms/view/A00218
Formal Axioms
First-Order Logic Definition
MaterialAliquot(x) ↔ MaterialEntity(x) ∧ ∃s(AliquotingProcess(s) ∧ isSpecifiedOutputOf(x, s))