growth factor
IRI: https://spec.industrialontologies.org/ontology/construct/GrowthFactor
Defined In: https://spec.industrialontologies.org/ontology/biopharma/MolecularEntity/
SubClass Of: organic molecular entity
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › bfo:independent continuant › bfo:material entity › molecular entity › organic molecular entity › growth factor
Definition
protein or peptide with a growth factor role
Semi-Formal Definition:
every instance of ‘growth factor’ is defined as exactly an instance of ‘peptide’ or ‘protein’ that ‘has role’ some ‘growth factor role’
Explanatory Notes
See the expanded definition under the corresponding role class.
Examples
- Vascular endothelial growth factor (VEGF) promoting endothelial proliferation; Insulin-like growth factor 1 (IGF-1) enhancing recombinant protein production in mammalian cells
Adapted From
- http://purl.obolibrary.org/obo/GO_0008083
Formal Axioms
First-Order Logic Definition
GrowthFactor(x) ↔ (Peptide(x) ∨ Protein(x)) ∧ ∃r (hasRole(x, r) ∧ GrowthFactorRole(r))
Description Logic
EquivalentTo: (constr:Peptide or constr:Protein) and constr:hasRole some constr:GrowthFactorRole
SubClassOf: constr:OrganicMolecularEntity