working solution role
IRI: https://spec.industrialontologies.org/ontology/construct/WorkingSolutionRole
Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaMaterial/
SubClass Of: bfo:role
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › bfo:specifically dependent continuant › bfo:realizable entity › bfo:role › working solution role
Definition
role held by a solution when the solution is prepared from a stock solution or intermediate stock solution at the concentration required for use in a planned process that is not itself a dilution process
Explanatory Notes
Working solutions are derived from stock solutions and adjusted to the concentrations required for assays, buffer systems, culture additives, or other procedures. They are intended for immediate or short-term use and are usually less concentrated than the stock from which they are prepared.
Examples
- 50 mM Tris-HCl prepared by diluting a 1 M Tris stock solution for use in an enzymatic assay
Counter-Examples
- A 1 M Tris-HCl stock solution stored for later dilutions
Adapted From
- https://www.fda.gov/regulatory-information/search-fda-guidance-documents/m10-bioanalytical-method-validation-and-study-sample-analysis and http://champ-project.org/images/ontology/cao.owl#CAO_000214
Primitive Class
This class is declared primitive and it does not have necessary and sufficient condiftions defined.
Primitive Rationale
There are insufficient constructs to create a set of necessary and sufficient conditions
Formal Axioms
First-Order Logic Axioms
WorkingSolutionRole(x) → Role(x) ∧ ∃s (Solution(s) ∧ roleOf(x, s))
Semi-Formal Natural Language Axioms
if x is a ‘working solution role’ then x is a ‘role’ that is the ‘role of’ some ‘solution’
Description Logic
SubClassOf: bfo:role
SubClassOf: constr:roleOf some constr:Solution