molecular indicator role
IRI: https://spec.industrialontologies.org/ontology/construct/MolecularIndicatorRole
Defined In: https://spec.industrialontologies.org/ontology/biopharma/MolecularEntity/
SubClass Of: molecular entity role
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › bfo:specifically dependent continuant › bfo:realizable entity › bfo:role › molecular entity role › molecular indicator role
Direct subclasses:
Definition
role held by a molecular entity when it is used or planned to be used so that an observable change in that molecular entity indicates the presence, amount, or condition of a particular material entity or quality
Explanatory Notes
The observable change is often visual (e.g., color change), but may also be a non-visual detectable signal (e.g., change in absorbance, change in electrical signal, or change in emitted or absorbed radiation)
Examples
- Phenol red bearing a molecular indicator role when its color change indicates pH in cell culture medium; Fluorescein-labeled molecule bearing a molecular indicator role when its fluorescence indicates binding or localization; Resazurin bearing a molecular indicator role when its reduction indicates cellular metabolic activity; pH indicator dye bearing a molecular indicator role when its color change indicates acidity or alkalinity; Redox indicator molecule bearing a molecular indicator role when its color change indicates oxidation-reduction state.
Adapted From
- http://purl.obolibrary.org/obo/CHEBI_47867
Primitive Class
This class is declared primitive and it does not have necessary and sufficient condiftions defined.
Primitive Rationale
There are insufficient constructs present to create a set of necessary and sufficient conditions
Formal Axioms
First-Order Logic Axioms
MolecularIndicatorRole(x) → MolecularEntityRole(x)
Semi-Formal Natural Language Axioms
if x is a ‘molecular indicator role’ then x is a ‘molecular entity role’