N4-glycosyl-L-asparagine
IRI: https://spec.industrialontologies.org/ontology/construct/N4GlycosylLAsparagine
Defined In: https://spec.industrialontologies.org/ontology/biopharma/MolecularEntity/
SubClass Of: N-glycosylated residue
Class Hierarchy
owl:Thing › bfo:entity › bfo:continuant › bfo:independent continuant › bfo:material entity › chemical moiety › amino acid residue › modified amino acid residue › glycoconjugated residue › glycosylated residue › N-glycosylated residue › N4-glycosyl-L-asparagine
Definition
N-glycosylated residue in which a glycan is covalently attached to the side-chain nitrogen of an L-asparagine residue
Explanatory Notes
The term “N4-glycosyl-L-asparagine” follows the classical IUPAC atom-numbering scheme, in which the side-chain amide nitrogen of L-asparagine is designated as N4. This nitrogen is the site of N-linked glycosylation.
Examples
- N4-glycosyl-L-asparagine residue in the Fc region of a monoclonal antibody; N4-glycosyl-L-asparagine residue carrying a complex N-linked glycan in a recombinant glycoprotein
Synonyms
- N-Glycosyl-L-asparagine
Adapted From
- http://purl.obolibrary.org/obo/MOD_00160 and http://purl.obolibrary.org/obo/CHEBI_59108
Primitive Class
This class is declared primitive and it does not have necessary and sufficient condiftions defined.
Primitive Rationale
This term is expected to remain primitive as the detailed treatment of chemical bonds, structure and formation is outside of the current scope of IOF. Other biological and chemical ontologies should be used for these purposes
Formal Axioms
First-Order Logic Axioms
N4GlycosylLAsparagine(x) → NGlycosylatedResidue(x)
Semi-Formal Natural Language Axioms
if x is an ‘N4-glycosyl-L-asparagine’ then x is an ‘N-glycosylated residue’