rocker bag

IRI: https://spec.industrialontologies.org/ontology/construct/RockerBag

Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaEquipment/

SubClass Of: container

Class Hierarchy

owl:Thing β€Ί bfo:entity β€Ί bfo:continuant β€Ί bfo:independent continuant β€Ί bfo:material entity β€Ί bfo:object β€Ί material artifact β€Ί container β€Ί rocker bag

Definition

container that is a flexible bag designed for rocking or wave-motion mixing, gently agitating its contents to provide mixing and gas transfer that enable controlled cultivation of cells or microorganisms under low-shear conditions

Explanatory Notes

1) Rocker bags are single-use or disposable flexible culture chambers typically made from inert plastic film. 2) They may be used with full rocker-motion bioreactors, as well as simpler incubator rockers or trays 3) Their design enables mixing and gas transfer by wave or rocking motion rather than by impellers, reducing shear stress.

Examples

  • Flexsafeβ€―RM bag

Adapted From

  • https://link.springer.com/chapter/10.1007/10_2008_15 and https://www.sartorius.com/en/products/fermentation-bioreactors/single-use-bioreactors/biostat-rm-flexsafe-rm

Primitive Class

This class is declared primitive and it does not have necessary and sufficient condiftions defined.

Primitive Rationale

There are insufficient constructs to create necessary and sufficient conditions, particularly for representing the flexible bag construction and the rocking or wave-motion configuration.

Formal Axioms

First-Order Logic Axioms

LA1:RockerBag(x) β†’ Container(x) ∧ βˆƒf (hasFunction(x, f) ∧ CellCultureHoldingFunction(f))
LA2: RockerBag(x) ∧ βˆƒb (Bioreactor(b) ∧ memberPartOfAtAllTimes(x, b)) β†’ BioreactorVessel(x)

Semi-Formal Natural Language Axioms

LA2: if x is a β€˜rocker bag’ and x is a β€˜member part of at all times’ some β€˜bioreactor’, then x is a β€˜bioreactor vessel’

if x is a β€˜rocker bag’ then x is a β€˜container’ that β€˜has function’ some β€˜cell culture holding function’

Description Logic


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