mobile phase
IRI: https://spec.industrialontologies.org/ontology/construct/MobilePhase
Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaEquipment/
SubClass Of: bfo:material entity
Class Hierarchy
owl:Thing βΊ bfo:entity βΊ bfo:continuant βΊ bfo:independent continuant βΊ bfo:material entity βΊ mobile phase
Definition
material entity with a mobile phase role
Semi-Formal Definition:
every instance of βmobile phaseβ is defined as exactly an instance of βmaterial entityβ that βhas roleβ some βmobile phase roleβ
Examples
- Water as mobile phase in reverse-phase chromatography; acetonitrile used as mobile phase in HPLC; phosphate buffer as mobile phase in ion-exchange chromatography; methanol serving as mobile phase in normal-phase chromatography; a water-acetonitrile mixture serving as the mobile phase during gradient elution; sodium chloride solution as mobile phase in size-exclusion chromatography
Counter-Examples
- Liquid used for column cleaning or sanitization after chromatography is completed; Air or nitrogen gas used for drying the column after elution (not used as percolating fluid during chromatography)
Adapted From
- http://purl.allotrope.org/ontologies/role#AFRL_0000011 and GE Protein Purification Handbook and https://goldbook.iupac.org/terms/view/M03952 and https://www.sartorius.com/en/knowledge/resources/chromatography-glossary
Formal Axioms
First-Order Logic Definition
MobilePhase(x) β MaterialEntity(x) β§ βr(MobilePhaseRole(r) β§ hasRole(x, r))
Description Logic
constr:MobilePhase β‘ bfo:material_entity β β constr:hasRole .constr:MobilePhaseRole
constr:MobilePhase β bfo:material_entity
EquivalentTo: bfo:material_entity and constr:hasRole some constr:MobilePhaseRole
SubClassOf: bfo:material_entity