critical material attribute
IRI: https://spec.industrialontologies.org/ontology/construct/CriticalMaterialAttribute
Defined In: https://spec.industrialontologies.org/ontology/biopharma/BiopharmaParameter/
SubClass Of: input material attribute
Class Hierarchy
owl:Thing βΊ bfo:entity βΊ bfo:continuant βΊ bfo:specifically dependent continuant βΊ input material attribute βΊ critical material attribute
Definition
quality or capability that is prescribed by an input critical material attribute specification
Semi-Formal Definition:
every instance of βcritical material attributeβ is defined as exactly an instance of βqualityβ or βcapabilityβ that is βprescribed byβ some βinput critical material attribute specificationβ
Explanatory Notes
See the expanded definition under the corresponding specification class. The term is formalized here as a defined class by referring to its corresponding specification class and exists primarily for ontological modeling and implementation convenience.
Examples
- manganese concentration in a chemically defined medium whose variation can affect glycosylation of the output material; glucose concentration in a feed medium whose variation can affect glycan profile of the output material;
Formal Axioms
First-Order Logic Definition
CriticalMaterialAttribute(x) β (Quality(x) β¨ Capability(x)) β§ βs(InputCriticalMaterialAttributeSpecification(s) β§ prescribedBy(x, s))
Description Logic
constr:CriticalMaterialAttribute β‘ (bfo:quality β constr:Capability) β β constr:prescribedBy .constr:InputCriticalMaterialAttributeSpecification
constr:CriticalMaterialAttribute β constr:InputMaterialAttribute
EquivalentTo: (bfo:quality or constr:Capability) and constr:prescribedBy some constr:InputCriticalMaterialAttributeSpecification
SubClassOf: constr:InputMaterialAttribute